Adonis

A new agonist monoclonal antibody targeting extracellular adenosine A2A receptor


BACKGROUND

Antibodies targeting Adenosin A2A receptor are used in fundamental and applied research. Nethertheless, main of them are polyclonaland more or less specific because of their epitope wich is intracellular: so, researchers often need to lyse cells and experimental material to obtain some results with this kind of antibodies.

 

KEY BENEFITS vs. STATE OF THE ART

Efficient and specific mAb:

Our mAb recognizes specifically the extracellular epitope of the Adenosin A2A receptor.

--> High value for diagnosis:

  • Easy to couple to an enzymatic biomarker (isotopicor fluorescent) for flow cytometry
  • Targets cells that express the Adenosin A2A receptor without lysing them.

APPLICATIONS

  • R&D diagnostics:
    • Diagnosis of hypoxia, syncop, kidney and heart failures, inflammatory diseases, septicemia,…
  • Therapeutics:
    • Potentially anti pain and anti inflammatory treatments

 

 

En savoir plus sur cette technologie

Axes & sous-axes :
Biothérapie, Santé & technologies du vivant

Etat Propriété Intellectuelle :
Transfert de Matériel

Partenariats :
Accord de Transfert de Matériel

Propriétaires :
Aix-Marseille Université, INSERM, Assistance Publique - Hôpitaux de Marseille

Maturité :