Background
Gap between the burden of infections due to multidrug-resistant bacteria and thedevelopment of new antibiotics to tackle the problem. More and more data on the role of antibiotics efflux in the multidrug resistant(MDR) bacteria emergence, but no efficient solution. → New molecules able to restore the sensitivity of MDR Bacteria to antibiotics (inhibitors of efflux pump). Already tested on 2 bacteria species andwith 3 antibiotics at different concentrations. At least 5 active moleculesincrease/restore in vitro antibiotics activity